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AIIHPC Structured Research Network APA Cycle 2 2019 Applied Partnership Awards Applying Research into Policy & Practice Postdoctoral Fellowships ARPP 2020 Cancer Prevention Fellowship Programme Cancer Prevention Fellowship Programme Reintegration Grant Capacity Building for Evidence Synthesis Clinical Research Facilities/Centres 2021 Cochrane Training Fellowships Collaborative Doctoral Awards Conference and Event Sponsorship Scheme COVID-19 2020 CSF 2020 DIFA - 2018 DIFA 2017 DIFA 2018 DIFA 2020 DIFA-2018 Doctoral Training Programme in Precision Medicine in Cancer Emerging Clinician Scientist Awards 2020 Emerging Investigator Awards Emerging Investigator Awards 2022 ERA-NET Cofund for Neuroscience Research (NEURON) ERA-NET Cofund for Personalised Medicine Framework for Safe Nurse Staffing and Skill Mix Fulbright-HRB Health Impact Awards Health Research Awards HRB Clinical Research Facilities HRB Collaboration in Ireland for Clinical Effectiveness Reviews HRB Postdoctoral Fellowships: ARPP 2023 HRB Postdoctoral Fellowships: CSF 2023 HRB Trials Methodology Research Network HRCI 2020 HRCI-HRB Joint Funding Scheme ICORG Statistics and Data Management Interdisciplinary Capacity Enhancement Awards Investigator Led Projects IPPOSI 2020 Irish Clinical Oncology Research Group Irish Platform for Patients Organisations Science and Industry Support Award Joint Programming Initiative Healthy Diet for a Healthy Life Joint Programming Initiative in Neurodegenerative Diseases Joint Programming Initiative on Antimicrobial Resistance Knowledge Exchange and Dissemination Scheme Knowledge Translation Awards Medical Research Charities Group Support Award MRCG-HRB Joint Funding Scheme National Children's Hospital Foundation Scheme National Clinical Trials Coordination Programme National integrated PhD programme for Medical Practitioners National Intellectual Disability Supplement to TILDA Patrick Quinn Awards for Parkinson's Research PPI Ignite Awards Project Development Grants Rare Diseases Research and Innovation Catalyst Awards (RDCat) 2023 RCQPS COVID-19 Research Collaborative for Quality and Patient Safety Research Collaborative in Quality and Patient Safety Research Training Fellowships for Healthcare Professionals RL FA 2020 RL PA 2020 Secondary Data Analysis Projects SFI-HRB-Wellcome Research Partnership Structured PhD Programme in Population Health and Health Services Research The Irish Longitudinal Study on Ageing Ulysses Research Visits US-Ireland R&D Partnership Awards WHO-SOLI-2020
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Host Institution
Atlantic Technological University DCU Department of Agriculture, Food and Marine Dublin City University Dublin Dental University Hospital Dublin Institute of Technology Economic and Social Research Institute Family Carers Ireland Fondazione Telethon Fraunhofer ITMP Health Information and Quality Authority Health Research Charities Ireland HSE - St. Luke's Hospital (Rathgar) Institute of Technology Sligo IPPOSI Irish Blood Transfusion Service, National Blood Centre Irish Clinical Oncology Research Group Ltd Irish Platform for Patients Organisations Science and Industry Irish Platform for Patients' Organisations, Science and Industry Ltd Irish Platform for Patients’ Organisations, Science and Industry Katholieke Universiteit Leuven Limerick Institute of Technology Maynooth University Medical Research Charities Group Ltd National University of Ireland Galway National University of Ireland, Galway Our Lady's Hospice Queen’s University Belfast RCSI Royal College of Physicians of Ireland Royal College of Surgeons in Ireland TCD Teagasc Technological University Dublin The Alzheimer Society of Ireland The Children's Hospital of Philadelphia Trinity College Dublin UCD University College Cork University College Dublin University Hospitals Leuven & KU Leuven University of Auckland University of California San Francisco University of Cambridge University of Galway University of Limerick University of Oxford UPMC Whitfield
Funding Awarded
18 awards
Advanced, automated compound screening for the identification of therapeutic agents in Multiple Sulfatase Deficiency.
Multiple Sulfatase Deficiency (MSD) is an extremely rare, fatal, yet untreatable condition. It is caused by the inherited deficiency of an enzyme (called FGE) that activates a whole family of 17 other cellular enzymes named sulfatases. Sulfatases are indispensable for the degradation of a subset of intracellular molecules. Thus,...
Progressing Sláintecare delivery from proposal to implementation: Insights from palliative care in Ireland
Sláintecare, Ireland’s national ten-year reform plan recommends universal healthcare. This represents the biggest Irish health system reform since its inception. Using palliative care as an example this project examines the development universal palliative care internationally and applies these learnings to Ireland.
Through a...
Measures of wellbeing for use in economic evaluation: valuing and assessing health outcomes in Ireland
In Ireland, healthcare decisions primarily concentrate on maximising health gain. However, with more integrated social care, there is growing recognition that this perspective is too narrow. Health maximisation is unlikely to be a relevant objective, particularly where demand for social care is high (e.g. in chronic diseases,...
Iron deficiency assessment for protection of the newborn brain
Iron deficiency is the most common nutritional deficiency in the world. About 1 in 4 people do not have enough iron to stay healthy. Pregnant women, infants and young children are at high risk of iron deficiency, as they need more iron than other population groups to support growth and development. Maternal health, including body...
Food industry corporate political activity and its potential influence on public health policy, research and practice in Ireland
In Ireland, non-communicable diseases (NCD), which include diabetes, cardio-vascular diseases and cancers, contribute to premature death and increased suffering and disability. Unhealthy diets, particularly those high in ultra-processed food products, and obesity, are one of the primary risks factors for NCD. Internationally...
Scenario and intervention modelling in Ireland for stroke: Evaluating the effect of alternative policy scenarios and interventions for stroke in Ireland on outcomes and costs
One in every four people in Ireland will have a stroke in their lifetime. People are less likely to die if they have a stroke than in previous decades, partly due to new treatments that prevent further strokes and improve outcomes. For every three people who survive their stroke, two acquire some type of disability such as...
Using knowledge translation to enhance the use of evidence in public health decision-making by policymakers and healthcare managers in Ireland
Health policy refers to decisions, plans, and actions that are undertaken to achieve specific health care goals within a society. Using high-quality evidence to inform how health policies are made is crucial to ensure safe and effective healthcare and to optimise patient and public health outcomes. Despite this, international research...
Hip fracture outcome recording and geographic equality
Hip fracture is a serious event in the lives of older people with around one in five individuals dying in the first year after their injury and many more losing their independence. Currently in Ireland, little is known about how people recover in the longer-term after hip fracture and many do not receive routine follow-up. In the last...
Reducing caesarean section rates in Ireland: a feasibility study and pilot randomised trial of an evidence-based intervention designed to reduce unnecessary caesarean section
Concern has been expressed globally at the rising caesarean section (CS) rate with a lack of evidence of any associated decrease in health problems for mothers and babies, indicating that many CSs are unnecessary. Maternal death and severe maternal health problems are trebled following CS compared with vaginal birth, and newborn babies...
A randomised placebo-controlled trial of low-dose aspirin initiated in the first trimester for optimising pregnancy outcome in pregestational diabetes
Pre-existing diabetes confers a high risk for adverse pregnancy outcome. High blood pressure disorders in pregnancy, including preeclampsia, are particularly common in this population and the combination of pre-existing diabetes and preeclampsia represents a notable high risk for poor pregnancy outcome, including stillbirth....
Improving outcomes for young adults with type 1 diabetes in Ireland: the D1 now feasibility and cluster randomised pilot study
Many young adults with type 1 diabetes find it hard to control their blood glucose levels. With many changes going on in their lives their diabetes is often not a priority. They also find it hard to engage with hospital diabetes services because of an inflexible clinic appointment system and seeing a different member of staff at each...
The SEA-CHANGE study: a pilot randomised controlled trial of the SElf-management After Cancer of the Head And Neck Group intErvention
Head and neck cancer (HNC) and its treatment are associated with specific challenges such as facial disfigurement and impairments in speech, breathing and swallowing, which can have a negative impact on wellbeing. Despite these burdens, there is a lack of psychosocial interventions to help HNC survivors live well with and beyond...
We Can Quit2: A cluster randomised pilot trial of a community-based smoking cessation intervention for women in disadvantaged areas of Ireland
Smoking rates remain high in Ireland despite considerable progress being made to reduce them in recent years. Ireland ranks second highest for smoking-related causes of death in the EU. Lung cancer, which is strongly linked to smoking, is now the most common cause of death for women in Ireland particularly those living in more...
Colchine for prevention of vascular inflammation in non-cardioembolic stroke (CONVINCE) - a randomised clinical trial of low-dose colchicine for secondary prevention of stroke. Northern Europe extension
Inflammation of the lining of arteries is an important factor contributing to clots, leading to heart attacks and strokes. Current studies are testing medicines traditionally used for inflammation of joints (arthritis) to prevent strokes and heart attacks. CONVINCE is a clinical trial, testing colchicine in low doses, a medicine used...
Feasibility of an intervention to improve attendance for diabetic retinopathy screening
Retinopathy is a serious and common condition affecting the sight of people with diabetes and it can cause blindness. It is preventable through screening and can be treated if found in time. However, the success of screening is dependent on people attending when invited. Studies show that a number of people with diabetes do not attend...
Low molecular weight heparin to prevent recurrent venous thromboembolism in pregnancy: a randomised trial of two doses: the HIGHLOW study
Women who are pregnant have an increased chance of developing blood clots. These clots can cause serious ill-health and can even be fatal. The death of a young mother is a tragic event with wide-reaching effects on the woman's family.
Women with a previous blood clot have a higher recurrence risk in pregnancy. In fact, the...Targeted therapeutic mild hypercapnia after resuscitated cardiac arrest: A phase III multi-centre randomised controlled trial
A cardiac arrest occurs when the heart stops pumping blood to the brain and other major organs. Approximately 10,000 people die from cardiovascular disease every year in Ireland. It is estimated that 5,000 of these deaths are from a sudden cardiac arrest. Early resuscitation (CPR) can get the heart pumping again but in many cases the...
Community Risk-based monitoring for Atrial Fibrillation Trial (CRAFT)
Atrial fibrillation, an irregular heart-beat, is common, affecting ~7% of people over 65 years of age. It is a major cause of stroke, increasing the risk of stroke 5-fold, and about one-third of patients with acute stroke have atrial fibrillation. Once detected, there are very effective treatments to prevent stroke - oral anticoagulant...