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Safety, cost and environmental impact of reprocessing low and moderate risk single-use medical devices: a systematic review

Objectives: Estimate the safety, financial and environmental impacts of reprocessing low and moderate risk single-use medical devices (SuMDs). Methods: Systematic review (PROSPERO ID: CRD42022365642) of primary studies of patients receiving reprocessed low and moderate risk SuMDs (non-critical and semi-critical medical devices a and b) versus first use of otherwise identical SuMDs. Items were sourced via database and […]

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Hexahydrocannabinol (HHC) use and harms in Ireland: new findings from the 2024 European Web Survey on Drugs

Background: Hexahydrocannabinol (HHC) is a semi-synthetic cannabinoid which was marketed and sold openly in Ireland as a legal alternative to cannabis products until it was controlled in July 2025. There have been reports of psychotic illness precipitated by HHC use. Consequently, there are fears that HHC may become a public health issue. This study’s aim […]

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Drug use prevalence in Ireland: Findings from recent population studies and estimates of problematic use

This is a supplement to Drugnet 92. Drugnet Ireland is the Health Research Board’s quarterly drug and alcohol research and policy newsletter. It provides summaries and analysis of recent publications and policy developments and well as overviews of particular issues relating to the drug and alcohol situation Ireland. Experts from the EUDA national focal point […]

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Effectiveness, safety, and cost-effectiveness of pharmacist prescribing

The HRB conducted a systematic review to synthesise evidence on the effectiveness, safety, and cost-effectiveness of pharmacist prescribing. This systematic review provides policy-makers in the Department of Health with evidence related to the safety, effectiveness, and cost-effectiveness of pharmacist prescribing compared with other prescribing healthcare professionals across primary, secondary, and tertiary healthcare settings. This evidence […]

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Polysubstance use in early adulthood and associated factors in the Republic of Ireland: an analysis of a nationally representative

Background and aims: Alcohol and other drug use is common in early adulthood; however, research on contemporary polysubstance use patterns—defined as use of multiple psychoactive substances—and their associated factors is limited. This study aimed to identify groups with differing polysubstance use patterns and to examine associations with individual, family and socio-environmental factors. Design: This is […]

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Trends in cocaine use and cocaine-related harms in Ireland: a retrospective, multi-source database study.

Background: Increased cocaine supply has coincided with increased global cocaine use. In 2019 Ireland had one of the highest last-year rates of cocaine use in Europe. However, there is a lack of data on the health-related impacts of cocaine use in European countries over time. Methods: This retrospective, multi-source database study utilised data from national […]

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Safety, cost and environmental impact of reprocessing high risk single-use medical devices: a systematic review and meta-analysis.

Abstract: Aim: To estimate the safety, financial and environmental effects of reprocessing high risk SUMDs. Methods: Systematic review (PROSPERO ID: CRD42022365642) of primary trial and observational studies of human participants receiving reprocessed high risk SUMDs compared with first use of identical SUMDs. Reprocessing was defined as cleaning, disinfection, and sterilisation or related procedures, and function […]

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Early and risky adolescent alcohol use independently predict alcohol, tobacco, cannabis and other drug use in early adulthood in Ireland: a longitudinal analysis of a nationally representative cohort

BACKGROUND: Early and risky adolescent alcohol use have each been associated with adult alcohol consumption. However, it remains unclear whether these behaviours independently predict later-life substance use when considered jointly, and research examining links with substances other than alcohol is limited. This study addresses these gaps by examining longitudinal associations between age at first alcohol […]

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