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EMERGE: A randomised placebo controlled trial of the Effectiveness of MEtformin in addition to usual care in the Reduction of GEstational diabetes mellitus effects
Diabetes (high blood sugars) that develops during pregnancy is called Gestational Diabetes Mellitus (GDM). GDM is increasing, affecting one-in-eight pregnant women in Ireland. Women with GDM have an increased risk of complications at the time of delivery, including Caesarean section. Women with GDM have a 7-fold increased risk of...
Cold air plasma to enhance hospital hygiene leading to reduced surface bacterial counts and patient acquisition of vancomycin-resistant enterococci and Clostridium difficile infection
Healthcare-associated infections (HCAI) affect 5-10% of patients admitted to an acute hospital but it is about three times higher in intensive care units (ICUs). Prevention involves many strategies but environmental hygiene is important as many bacterial causes persist on horizontal surfaces, e.g. methicillin-resistant Staphylococcus...
Oral flucloxacillin alone versus flucloxacillin and phenoxymethylpenicillin for the emergency department outpatient treatment of cellulitis: a non-inferiority randomised controlled trial
Acute bacterial skin and skin structure infections (ABSSSIs) are commonly encountered in Emergency Departments (EDs). In Ireland, the most common ABSSSI is cellulitis, which is a spreading bacterial infection of the skin and tissues beneath the skin. Approximately 12 in every 1,000 ED patient attendances in Ireland is due to...