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Funding Awarded
2 awards
Prevention of postoperative persistent bowel symptoms in patients with Hirschsprung's Disease
Hirschsprung's disease (HD) is a relatively common cause of intestinal obstruction in the new-born, occurring in 1 in 4,000 live births. It is characterised by abnormal development of the nerve supply to varying lengths of the large bowel prior to birth. The gold standard treatment for HD is an operation to remove the diseased bowel...
Genetic basis of reflux nephropathy-related hypertension and renal failure in children
Vesicoureteric reflux (VUR) is the backflow of urine from the bladder towards the kidneys. It is a common disorder in children, but is often not diagnosed because it may have no symptoms. In some children, it stops happening as they grow, and they suffer no ill effects. However, it can be associated with kidney damage, and is a major...