Role of TWEAK/Fn14 pathway in mediating muscle pathology in SMA

Spinal muscular atrophy (SMA) is a devastating disease caused by loss of both nerve cells and muscle function. While the nerve is the major affected cell type, therapies specifically aimed at improving muscle function ameliorate survival and/or symptoms in SMA models. Thus,developing muscle-

Award Date
01 July 2016
Award Value
Principal Investigator
Professor Melissa Bowerman
Host Institution
University of Oxford
MRCG-HRB Joint Funding Scheme