Label free monitoring of fibrinogen levels in human blood plasma using asymmetric imides
The project aims to develop new methodologies for analysis of blood plasma samples using vibration spectroscopy (infrared and Raman spectroscopy) as alternative to the time consuming, costly and poorly reliable Clauss assay, commonly used in hospitals. Two different aspects will be addressed, (i) requirement for optimisation of experimental conditions, including sample preparation protocols, (ii) development and evaluation of data-mining approaches (means of multivariate analysis) for the specific quantification of plasma fibrinogen. Reagent-free molecular spectroscopy techniques (infrared and Raman) could lead to the next generation of new diagnostic tools usable as a routine screening technique in the clinical environment.
- Award Date
- 01 January 2018
- Award Value
- €2,500.00
- Principal Investigator
- Dr Jennifer McIntyre
- Host Institution
- Dublin Institute of Technology
- Scheme
- Ulysses Research Visits