Filter By:
- Year
-
Scheme
AIIHPC Structured Research Network APA Cycle 2 2019 Applied Partnership Awards Applied Research Projects in Dementia Applying Research into Policy & Practice Postdoctoral Fellowships ARPP 2020 Cancer Prevention Fellowship Programme Cancer Prevention Fellowship Programme Reintegration Grant Capacity Building for Evidence Synthesis Clinical Research Facilities/Centres 2021 Cochrane Training Fellowships Collaborative Doctoral Awards Conference and Event Sponsorship Scheme COVID-19 2020 CSF 2020 DIFA - 2018 DIFA 2017 DIFA 2018 DIFA 2020 DIFA-2018 Emerging Clinician Scientist Awards 2020 Emerging Investigator Awards Emerging Investigator Awards for Health (EIA) 2022 Emerging Investigator Awards Full ERA-NET Cofund for Neuroscience Research (NEURON) ERA-NET Cofund for Personalised Medicine EU Joint Programming Initiative Framework for Safe Nurse Staffing and Skill Mix Health Research Awards Health Research Awards - Definitive Intervention Health Research Awards - Definitive Interventions Health Research Centre HRB Clinical Research Coordination Ireland HRB Clinical Research Facilities HRB Collaboration in Ireland for Clinical Effectiveness Reviews HRB Trials Methodology Research Network HRCI 2020 HRCI-HRB Joint Funding Scheme ICORG Statistics and Data Management Interdisciplinary Capacity Enhancement Awards Investigator Led Projects IPPOSI 2020 Irish Clinical Oncology Research Group Irish Network for Research in Dementia and Neurodegeneration Irish Platform for Patients Organisations Science and Industry Support Award Irish Platform for Patients' Organisations, Science and Industry Joint Programming Initiative Healthy Diet for a Healthy Life Joint Programming Initiative in Neurodegenerative Diseases Joint Programming Initiative on Antimicrobial Resistance Knowledge Exchange and Dissemination Scheme Knowledge Translation Awards Medical Education Research Grant Medical Research Charities Group Support Award MRCG-HRB Joint Funding Scheme National Children's Hospital Foundation Scheme National Clinical Trials Coordination Programme National integrated PhD programme for Medical Practitioners National Intellectual Disability Supplement to TILDA National SpR Academic Fellowship Programme/HRB Joint Funding Scheme National SpR/SR Academic Fellowship Programme Patrick Quinn Awards for Parkinson's Research PPI Ignite Awards Project Development Grants Project Development Grants in Cancer Nursing Research RCQPS COVID-19 Research Collaborative for Quality and Patient Safety Research Collaborative in Quality and Patient Safety Research Leader Awards Research Training Fellowships for Health Professionals Research Training Fellowships for Healthcare Professionals RL FA 2020 RL PA 2020 Secondary Data Analysis Projects SFI-HRB-Wellcome Biomedical Partnership SFI-HRB-Wellcome Research Partnership Structured PhD Programme in Population and Health-Services Research Education Structured PhD Programme in Population Health and Health Services Research The Irish Longitudinal Study on Ageing Trials Methodology Research Network Ulysses Research Visits US-Ireland R&D Partnership Awards WHO-SOLI-2020
-
Host Institution
Alpha One Foundation Athlone Institute of Technology Beaumont Hospital Cystinosis Foundation Ireland DCU Department of Agriculture, Food and Marine Dublin City University Dublin Dental University Hospital Dublin Institute of Technology Economic and Social Research Institute Fighting Blindness Fondazione Telethon Fraunhofer ITMP Health Information and Quality Authority Health Research Charities Ireland HSE - Letterkenny General Hospital HSE - Midland Regional Hospital at Tullamore HSE - St. Luke's Hospital (Rathgar) Institute of Technology Sligo IPPOSI Irish Blood Transfusion Service, National Blood Centre Irish Cancer Society Irish Clinical Oncology Research Group Ltd Irish Platform for Patients Organisations Science and Industry Irish Platform for Patients' Organisations, Science and Industry Irish Platform for Patients' Organisations, Science and Industry Ltd Irish Platform for Patients’ Organisations, Science and Industry Irish Thoracic Society Katholieke Universiteit Leuven Limerick Institute of Technology Mary Immaculate College Limerick Maynooth University Medical Research Charities Group Ltd Molecular Medicine Ireland National Rehabilitation Hospital National Suicide Research Foundation National University of Ireland Galway National University of Ireland, Galway National University of Ireland, Maynooth Our Lady's Hospice RCSI Royal College of Physicians of Ireland Royal College of Surgeons in Ireland Royal Victoria Eye and Ear Hospital Research Foundation Ltd St John of God's Research Foundation Limited St. James's Hospital TCD Teagasc Technological University Dublin The Alzheimer Society of Ireland The Children's Hospital of Philadelphia The Children's Medical and Research Foundation Trinity College Dublin UCD University College Cork University College Dublin University Hospitals Leuven & KU Leuven University of Auckland University of California San Francisco University of Cambridge University of Galway University of Limerick University of Oxford
Funding Awarded
29 awards
A functional genomics pipeline for genetic discovery in diabetic kidney disease
Diabetes is responsible for a large proportion of chronic kidney disease (CKD), end-stage kidney disease (ESKD), blindness, amputation, heart disease and stroke. Tight glycemic control in type 1 diabetes (T1D) or type 2 diabetes (T2D) can delay or arrest the progression of microvascular complications. How hyperglycemia...
Interrogating Steroid Non-responsiveness in the Irish Eosinophilic Oesophagitis Population
Eosinophilic oesophagitis (EoE) is a rare, increasingly recognised disease where an immune cell (eosinophil) builds up in the oesophagus in response to allergens including foods. This damage can lead to vomiting, abdominal pain, difficulty swallowing, blockage, and with time scaring which may need surgery. EoE is a serious affliction...
Co-producing actionable knowledge to strengthen cultural humility in Irish mental health services
Research tells us that ethnic minority populations experience mental health difficulties at an unequal rate compared to the general population and experience great difficulties getting their mental healthcare needs met. Human rights law and mental health policy state that everyone must get their mental healthcare needs met. People have...
Investigation of hospital sanitary ware as reservoirs of persistent antimicrobial resistant pathogens and links to bloodstream infections: Implications for infection prevention and control
Infections caused by bacteria lengthen patient stays in hospital and increase the complexity of treating the patient. These bacteria are frequently antibiotic resistant superbugs, like MRSA or CPE. Once the bacteria is in a patient it is a danger to the patients' health. These bacteria can survive and live outside the human body in...
Enhancing healthcare transition and longitudinal care for adolescents and adults with spina bifida and/or hydrocephalus in Ireland
Spina Bifida (SB) and hydrocephalus are lifelong conditions. Many people who have SB will also have hydrocephalus. While there are a number of supports and care plans for children with SB and/or hydrocephalus in Ireland, transitioning into adult care may pose problems. This project will investigate the experiences of those affected by...
Intervention of antimicrobial resistance transfer into the food chain (INART)
Joint Programming Initiative on Antimicrobial Resistance (JPIAMR)
Soil and water have been identified as reservoirs of antimicrobial resistance (AMR) and the food chain as the most likely mode of AMR transfer into human and animal pathogens. Manure is reused as soil fertiliser in which food plants grow and is a source of AMR....The LinKT (Linking into Knowledge Translation) project: connecting, integrating and translating evidence to make a difference for families
Increasing evidence highlights the effectiveness of early intervention and prevention parenting interventions for improving the mental health and wellbeing of parents and children in the earliest years. However, these are often complex, difficult to implement effectively and fail to reach the most vulnerable families. Accessible,...
Novel immune targets in Multiple Sclerosis
In Multiple Sclerosis Interferonb has been used as a first line treatment regimen for the past 15 years and many patients have shown therapeutic benefit and continue to do so from this 'natural' immune modulator. However, for others interferonb shows no clear therapeutic benefit and we are looking into how to change these patients into...
Comparative mass spectrometric profiling of the dystrophin complexome in normal versus pathological muscles with differing degrees of fibre degeneration
Duchenne muscular dystrophy is the most commonly inherited neuromuscular disease of early childhood. The disorder affects almost exclusively boys due to the fact that the defective gene is located on the X-chromosome. The skeletal musculature, the respiratory system,the heart and the central nervous system are majorly affected in...
Perspectives of partners of women who experience mental health issues in the postnatal period
For most families having a baby is a happy occasion. A small number of women, however, suffer from mental health issues following the birth of their baby. Often the womans partner can play an important role in seeking help and supporting the woman and the baby. However, we have very little information on how the partners of women who...
The ExACT Trial
Exercise therapy is a well established, effective treatment for individuals with chronic pain and Acceptance and Commitment Therapy (ACT) is a promising new approach in the management of chronic pain. ACT helps people with chronic pain to focus on awareness of personal values and promotes activity that will enhance their quality of...
SDHB and its role in epigenetic alteration in malignant phaeochromocytoma
A phaeochromocytoma (PC) refers to a tumour located on the adrenal gland, which releases adrenaline and similar hormones and causes high blood pressure (in severe cases this may be fatal). When a similar tumour occurs outside of the adrenal gland it is called a paraganglioma (PGL) and can be located anywhere from skull to pelvis....
The Irish kidney gene project - identification and characterisation of novel genetic causes of familial kidney disease
Certain kidney diseases tend to run in families, suggesting that particular genes are inherited from one generation to the next, causing kidney disease. By undertaking a joint training programme between with Trinity College Dublin and Harvard Medical School Boston, I plan to study these families and seek to identify specific genes that...
Use of software and computer technology in aphasia rehabilitation; investigating issues of efficacy, usability and cost effectiveness
Technology can provide an answer for over-stretched health care provision but will service users, particular older adults, actively engage with it? This research will investigate the benefits of a computer programme on language comprehension abilities (i.e. ability to understand spoken sentences) and explore the user experience of...
Development and validation of metric-based training to proficiency for dental implant placement
Common dental diseases such as dental decay (caries) and gum (periodontal) disease can lead to the loss of teeth, which has detrimental effects on patients chewing ability, speech and smile. While retaining teeth for patients is a primary goal for the dental profession, the replacement of teeth when they are lost is an important role...
Characterisation of polyclonal IgG and paraprotein glycosylation in multiple myeloma to investigate structural and functional insights into stage-specific pathologies
Multiple myeloma is a type of blood cancer characterized by abnormal antibody called paraprotein, produced by the cancerous plasma cells in the bone marrow. Patients develop anaemia (due to bone marrow infiltration by cancerous cells), high calcium, bone destruction, kidney failure and death. Survival has improved since the approval of...
Unwrapping the layers of complexity of clinical performance assessment of physiotherapy students and identifying key stakeholders' preferences towards enhancing the process
Clinical performance assessment of health professional students is imperative as it provides a measure of a students readiness to practice within their profession. However, it is widely acknowledged as being inherently problematic. Difficulties reported by clinicians in medicine, nursing, psychology and social work include the...
Caesarean section in nulliparous women: factors influencing decision-making process and outcomes for women- The MAMMI study caesarean section strand
This study will find out the factors, or combination of several factors, that influence the decision to perform a caesarean section (CS) in first-time mothers in Ireland, the health problems women experience in the first year after the birth and what women, midwives and obstetricians believe are the reasons behind the decision to...
Towards personalised therapy in stricturing crohn's disease- exploring and exploiting the role of NADPH oxidase in intestinal fibrosis
Crohn's disease, a member of the family of inflammatory bowel diseases, causes inflammation throughout the digestive tract and frequently results in fibrosis (scarring) of the intestine, which will cause narrowing and ultimately bowel obstruction. Available treatments can dampen the inflammation, but do not prevent fibrosis. It is...
An investigation into early adverse life events and psychotic-like experiences in Irish youth
At some time in their life, up to one in six adolescents is likely to have experienced some form of hallucinations or delusions, also known as psychotic-like experiences. These experiences include things like hearing voices, seeing things that are not there and having fixed false beliefs about yourself or the world around you. Most...
Attenuation of exaggerated post-prandial gut hormone response: A novel therapeutic strategy for the treatment of excessive weight loss among disease-free post-oesophagectomy patients
There is increasing incidence of cancer of the oesophagus (the gullet or swallowing tube). Improvements to treatment strategies for oesophageal cancer have produced an increasing population of patients who remain free from the disease recurrence in the long-term. Optimising long-term outcomes for these patients after treatment...
The clinical application of immunometabolism to the TB Patient
Recent studies have shown that cells of the immune system change the way that they break down sugars (their metabolism) after they are stimulated, and that this change in metabolism is needed in order to produce specific chemicals (cytokines) that fight infection.
We will study what metabolism changes happen in immune cells from...Investigating the impact of body composition and nutritional intervention strategies in pancreatic cancer
Pancreatic cancer is the 9th most common cancer in Ireland, and the 5th most common cause of cancer related death. Because of its location deep within the abdomen, patients often present with advanced cancer at the time of diagnosis. The options for treatment are limited as surgery is only suitable for patients who don't have spread of...
Overcoming survival signalling in Multiple Myeloma
Multiple Myeloma (MM) is a blood cancer affecting plasma cells, a type of white blood cell located in the bone marrow. It affects the bones, kidneys and causes patients to have frequent infections. There are approximately 250 new cases diagnosed in Ireland annually. MM is not curable and although the treatment for this condition...
Living with Motor Neurone Disease (MND) and Dysphagia -the personal experiences of individuals with MND and their caregivers
Motor Neurone Disease (MND) is one of the most progressive diseases of the nervous system, for which there is no cure. It often leads to weakness in the arms, hands and legs, posing difficulties with daily life activities. Throat muscles can also be affected leading to speech and swallowing problems (dysphagia). Dysphagia can be life...
Development of a core set of clinical care provision indicators for non-specialist palliative care in the acute care hospital setting
Palliative care encompasses the support structure around people facing problems associated with life-limiting illness and includes the support of their families, but this is more than end-of-life care, and is viewed as central component of care for people living with limiting illnesses. Palliative care policies in Ireland draw on these...
The OPTIMAL study: A randomized controlled trial and process evaluation of an OccuPaTIonal therapy led self MAnagement support programme for patients with muLtimorbidity in primary care
Many people with chronic disease tend to have more than one chronic condition, referred to as multimorbidity. It is predicted that the number of individuals with multimorbidity is set to increase substantially in the future due to the growing elderly population. Those with multimorbidity experience poor physical function and find it...
HRB Clinical Research Coordination Ireland
Clinical Research Facilities and Centres (CRF/Cs) have been developed in each of the five applicant universities, providing the infrastructure and specialist staff to facilitate collaborative research but they lack an overarching support structure with which to coordinate multicentre clinical trial activities. One key exception is...
Overcoming mechanism of treatment resistance in castration-resistant prostate cancer: Defining a new treatment paradigm
Prostate cancer is the second leading cause of male cancer mortality in Ireland: in 2012, 533 men died from this disease.Prostate cancer growth is stimulated by male sex hormones (androgens) e.g. testosterone. The mainstay of initial treatment is to block gonadal production of these hormones. However, with time, cancers develop other...