Funding Awarded

Early Detection and Intervention for Cerebral Palsy (EDI4CP).

Public and Patient Involvement (PPI) in research is a key focus of our active award, the HRB Irish Network for Children’s Clinical Trials (In4kids). We are now seeking KTA funding for a 0.6FTE PPI coordinator dedicated to our Cerebral Palsy (CP) Research programme in the network. This is a new national programme that will be rolled out...

Co-creation of a cookery book - pathways to making changes in diet

Personalized nutrition is based on the idea that individualizing nutritional advice will be more effective than more generic approaches. Studies are showing successful outcomes by applying such methods. Our group has been involved in several human intervention studies where dietary advice is given to participants based on their...

Medication without harm: Building a network and knowledge exchange programme.

The World Health Organisation (WHO) has a Global Patient Safety Challenge: ‘Medication Without Harm’ which aims to reduce worldwide harm associated with medications by half over 5 years. Medication-related harm includes medication incidents, errors, adverse drug reactions (ADRs; harmful responses to medicine) and adverse drug events...

PARKIE: Parkinson's community Awareness of Research; emphasis on Knowledge and Information Exchange.

Our lab is studying the role of our immune system in the development of Parkinson's. Our immune system protects the body against attacks from viruses and bacteria but, when we look at blood samples of people with Parkinson's, we can see they have an increased amount of one immune cell type, namely a type of T-cell called Th17 cells. In...

Art4Knowledge – Art Therapy for Knowledge Exchange between UCC CTG patients with cancer, their families, and clinical trials teams.

Art4Knowledge expands on efforts of the HRB-funded UCC Cancer Trials Group (UCC CTG), which provides access via clinical trials to cutting edge treatments and supportive care for patients with cancer in the South of Ireland. UCC CTG connects UCC research teams with clinical trials units in Cork University Hospital, University Hospital...

Psychosis in the Theatre

This project is about enhancing our public patient involvement (PPI) activities within our Clinical Doctoral Award (CDA) programme by using the Arts to give voice to and tell the story of the collective of people who are affected by psychosis. Our CDA, PSI-STAR (Psychosis Ireland Structured Training and Research Programme) includes...

Taking a World Cafe approach to improving understanding of psychosis and establishing a psychosis research PPI network

The primary aim of this project is to establish a psychosis research PPI network in Ireland. This will be done via a process of meaningful engagement and dialogue with people with lived experience of psychosis and other individuals and organisations with an interest in psychosis.

Specifically, we propose to host a series of...

Clinical trials: what are they and why are they important.

Randomised trials are an important research design and can provide reliable and robust evidence on the benefits, harms and costs of health care. Substantial public and charitable funding is allocated to clinical trials every year. However, there are concerns that much of this is wasted.1 The reasons for such waste include inadequate...

National Patient Education and Research Engagement Programme.

Inflammation is a critical process in fighting infection. However, if uncontrolled, it can contribute to the development of autoimmune disease, including inflammatory forms of arthritis, which cause joint destruction and disability. Medicines available for patients with RA have improved a lot over the last 15-years, however a...

Better Osteoarthritis Care: Delivering education and training for primary care health professionals in Ireland.

Osteoarthritis is the most common form of arthritis in Ireland. It is a condition of the joints that can cause pain, reduce mobility and result in poorer quality of life. It is more common in people over the age of 50 and often affects the knee and hip joints. To ensure that people with osteoarthritis receive ideal care, it is...

Developing an online platform to promote oral health among the Cystic Fibrosis community.

This KTA will be used in order to disseminate findings from our research into the oral health of people with Cystic Fibrosis (PWCF). We seek to provide information and education to two groups of people: 1. PWCF and parents/guardians of PWCF, and 2. Oral Healthcare Professionals. 

We will engage with patient advocates from...

Integrated Knowledge Translation for Advanced Therapies: From Bench to Bedside.

The value of clinical research is to improve treatment outcomes for patients and to inform health policy.  However, the knowledge gained from research only translates into impact for patients when new therapies become used as part of routine practice. 

Advanced therapy medicinal products (ATMPs) are...

HD-knowhow.

A rare disease is a health condition that affects a small number of people compared with other prevalent diseases in the general population. Empirical research shows that patients with severe illnesses prefer the physician to dominate decision processes and provide the information needed. However, in rare diseases, due to the low...

Translating knowledge into care to enhance sensory-cognitive health of people in longterm care in Ireland

This Knowledge Translation (KT) project will convert our research into practice to improve sensory-cognitive health in residents with dementia (RwD) in nursing homes in Ireland.  We are currently conducting a pilot clinical trial (‘SENSE-Cog Residential Care’) to evaluate whether enhancing sensory health (i.e. hearing/vision) in...

FUTURE-VASC

This project, FUTURE-VASC, aims to share knowledge from a research study called FAIRVASC, so that more people can benefit beyond the life of the original award. FAIRVASC has united scientists, clinicians and patients across Europe in a common goal of linking together data from several vasculitis registries (databases) to create one...

Building Circles of Support for people with intellectual disabilities.

The overall aim of the project is to use research information to develop resources to enhance the Circles of Support (COS) for adults with intellectual disabilities that can be used in person-centred planning processes. Person-centred planning puts the individual with intellectual disability at the centre of the process, and builds...

Translating the tailoring process to improve the implementation of diabetes care.

Our application supports the CUSTOMISE project funded by a HRB Research Leader Award. Our project which is looking at how to implement effective programmes in the health service in a way that is acceptable and practical for health professionals and service users. One such programme is the DAFNE self-management programme for adults with...

Educating the Irish Public on Genomics

The exploration of the human genome is one of the defining medical ethical issues of our time. It has both the potential to improve and save countless human lives, but doesn’t come without risk.  As genomics enters the Irish public's eye, there is a recognised need for efforts to educate the public here in Ireland about the...

Pandemic Resilience- translating knowledge for improved future pandemic preparedness.

Since 2015, the HRB-Irish Critical Care-Clinical Trials Network has established a research program in preparation for pandemics. As part of this, we assessed the barriers and developed solutions to conducting research during a future global pandemic. This work led to a coordinated Irish and global response to COVID-19 with a programme...

TAME-Translation: Translating the TAME cardiac arrest trial results to public, policy, clinicians and researchers.

People who survive sudden out-of-hospital cardiac arrest (OHCA) usually require intensive care unit (ICU) treatment. The ‘TAME’ cardiac arrest trial, co-led by the Irish Critical Care-Clinical Trials Network (ICC-CTN), has just completed, including 1700 ICU patients from Ireland and 17 countries worldwide. TAME looked at a novel...

CURRENT-KTA | Recurrent Miscarriage: evaluating CURRENT services-Knowledge Translation Acceleration.

Through this RE:CURRENT-KTA application we aim to work with knowledge users to raise awareness, share knowledge, and facilitate practice change to maximise the impact of the RE:CURRENT (Recurrent miscarriage: evaluating CURRENT services) Project and provide more effective healthcare services for people with recurrent miscarriage. We...

Tip of the iceberg: highlighting the long term health consequences of polycystic ovary syndrome.

Polycystic ovary syndrome (PCOS) is a chronic health condition that affects up to 15% of all women. It is characterised by increased blood levels of hormones called androgens (such as testosterone), alongside irregular periods and multiple follicles on the ovaries on ultrasound. PCOS has traditionally been perceived as a purely...

The Ignition study: Sharing stories to improve the experience of transition for young people with cerebral palsy

Cerebral palsy (CP) is a common cause of disability among children. All people with CP have a physical impairment. About 30% use a wheelchair and some children also have difficulties hearing, seeing and speaking. Children with CP are transferred from children’s health services to adult services at age 18. This can be challenging as...

Enhancing Testicular Awareness and Self-Examination Among Gay Men: Campaign Co-Design and Delivery Using the World Café Methodology.

Purpose 

To design and deliver a community-based campaign to promote testicular awareness and self-examination among gay men.

Importance 

In comparison to straight men, gay men are more likely to report a cancer diagnosis including testicular cancer, the most common...

Co-design and co-adaptation of a trustworthy online resource for healthcare professionals and people with chronic hip and knee pain in Ireland

Long-term, painful conditions of the hip and knee joint are common in Ireland. Yet, many patients sit on waiting lists for months or years, even when specialist opinions are not needed. In the meantime, pain gets worse, affecting ability to live, work and be fully active. Expert knowledge on how to exercise with these conditions and...

Teaching & Learning Trauma Informed Care for Health Settings.

While most people have experienced some form of psychological trauma at some point in their life, severe psychological trauma is particularly common in people who are socially excluded (i.e., through homelessness, addiction, poverty, incarceration and/or belonging to minority ethnic groups). Accessing healthcare in hospitals for those...

Plasma-based therapies for bone infection

Orthopaedic infection is life-threatening and current treatments are only sparingly successful. Despite aggressive peri-operative antibiotic treatments, 1.5% of knee revisions, 0.7 to 11.9%, of spinal infections (depending on the complexity of the procedure) and up to 27% of open fractures become infected. Moreover, the complexity of...

Prediction of radiation toxicity in prostate cancer patients using Raman spectroscopy

There are no tests currently available to predict an individual patient's response to radiotherapy. Some patients experience severe long term side effects months and even years after their treatment has finished and these effects can be permanent. For example, some prostate cancer patients develop life-changing bowel and urinary...