Filter By:
- Year
-
Scheme
AIIHPC Structured Research Network APA Cycle 2 2019 Applied Partnership Awards Applied Research Projects in Dementia Applying Research into Policy & Practice Postdoctoral Fellowships ARPP 2020 Cancer Prevention Fellowship Programme Cancer Prevention Fellowship Programme Reintegration Grant Capacity Building for Evidence Synthesis Clinical Research Facilities/Centres 2021 Cochrane Training Fellowships Collaborative Doctoral Awards Conference and Event Sponsorship Scheme COVID-19 2020 CSF 2020 DIFA - 2018 DIFA 2017 DIFA 2018 DIFA 2020 DIFA-2018 Emerging Clinician Scientist Awards 2020 Emerging Investigator Awards Emerging Investigator Awards 2022 ERA-NET Cofund for Neuroscience Research (NEURON) ERA-NET Cofund for Personalised Medicine EU Joint Programming Initiative Framework for Safe Nurse Staffing and Skill Mix Fulbright-HRB Health Impact Awards Health Research Awards Health Research Awards - Definitive Intervention Health Research Awards - Definitive Interventions Health Research Centre HRB Clinical Research Coordination Ireland HRB Clinical Research Facilities HRB Collaboration in Ireland for Clinical Effectiveness Reviews HRB Trials Methodology Research Network HRCI 2020 HRCI-HRB Joint Funding Scheme ICORG Statistics and Data Management Interdisciplinary Capacity Enhancement Awards Investigator Led Projects IPPOSI 2020 Irish Clinical Oncology Research Group Irish Network for Research in Dementia and Neurodegeneration Irish Platform for Patients Organisations Science and Industry Support Award Irish Platform for Patients' Organisations, Science and Industry Joint Programming Initiative Healthy Diet for a Healthy Life Joint Programming Initiative in Neurodegenerative Diseases Joint Programming Initiative on Antimicrobial Resistance Knowledge Exchange and Dissemination Scheme Knowledge Translation Awards Medical Education Research Grant Medical Research Charities Group Support Award MRCG-HRB Joint Funding Scheme National Children's Hospital Foundation Scheme National Clinical Trials Coordination Programme National integrated PhD programme for Medical Practitioners National Intellectual Disability Supplement to TILDA National SpR Academic Fellowship Programme/HRB Joint Funding Scheme National SpR/SR Academic Fellowship Programme Patrick Quinn Awards for Parkinson's Research PPI Ignite Awards Project Development Grants Project Development Grants in Cancer Nursing Research RCQPS COVID-19 Research Collaborative for Quality and Patient Safety Research Collaborative in Quality and Patient Safety Research Leader Awards Research Training Fellowships for Health Professionals Research Training Fellowships for Healthcare Professionals RL FA 2020 RL PA 2020 Secondary Data Analysis Projects SFI-HRB-Wellcome Biomedical Partnership SFI-HRB-Wellcome Research Partnership Structured PhD Programme in Population and Health-Services Research Education Structured PhD Programme in Population Health and Health Services Research The Irish Longitudinal Study on Ageing Trials Methodology Research Network Ulysses Research Visits US-Ireland R&D Partnership Awards WHO-SOLI-2020
-
Host Institution
Alpha One Foundation Athlone Institute of Technology Beaumont Hospital Cystinosis Foundation Ireland DCU Department of Agriculture, Food and Marine Dublin City University Dublin Dental University Hospital Dublin Institute of Technology Economic and Social Research Institute Fighting Blindness Fondazione Telethon Fraunhofer ITMP Health Information and Quality Authority Health Research Charities Ireland HSE - Letterkenny General Hospital HSE - Midland Regional Hospital at Tullamore HSE - St. Luke's Hospital (Rathgar) Institute of Technology Sligo IPPOSI Irish Blood Transfusion Service, National Blood Centre Irish Cancer Society Irish Clinical Oncology Research Group Ltd Irish Platform for Patients Organisations Science and Industry Irish Platform for Patients' Organisations, Science and Industry Irish Platform for Patients' Organisations, Science and Industry Ltd Irish Platform for Patients’ Organisations, Science and Industry Irish Thoracic Society Katholieke Universiteit Leuven Limerick Institute of Technology Mary Immaculate College Limerick Maynooth University Medical Research Charities Group Ltd Molecular Medicine Ireland National Rehabilitation Hospital National Suicide Research Foundation National University of Ireland Galway National University of Ireland, Galway National University of Ireland, Maynooth Our Lady's Hospice RCSI Royal College of Physicians of Ireland Royal College of Surgeons in Ireland Royal Victoria Eye and Ear Hospital Research Foundation Ltd St John of God's Research Foundation Limited St. James's Hospital TCD Teagasc Technological University Dublin The Alzheimer Society of Ireland The Children's Hospital of Philadelphia The Children's Medical and Research Foundation Trinity College Dublin UCD University College Cork University College Dublin University Hospitals Leuven & KU Leuven University of Auckland University of California San Francisco University of Cambridge University of Galway University of Limerick University of Oxford
Funding Awarded
23 awards
PSychosis Ireland Structured Training and Research programme (PSI-STAR)
Psychotic disorders, such as schizophrenia and bipolar disorder, occur in about 3 in a hundred people and usually start in adolescence or young adulthood, greatly disrupting a young person's life in terms of education, social relationships and career outcomes. Because of the early age of onset and...
Collaboration Agreement to Establish a Research Collaborative for Quality and Patient Safety Phase III
The Research Collaborative in Quality and Patient Safety (RCQPS) is a collaborative initiative between the Health Research Board, the Health Service Executive, National Quality Improvement Team and the Royal College of Physicians of Ireland. It was established in 2013 to advance nationally relevant research in the area of quality and...
Defining the consequences of innate immune training on protective versus pathogenic T cell responses in patients with tuberculosis.
Tuberculosis (TB) ranks alongside HIV as the world's most deadly infectious disease, killing 1.5 million people every year. It is caused by the bacteria Mycobacterium tuberculosis (Mtb), which primarily infects people's lungs. Treating this disease is becoming more difficult due to antibiotic-resistant Mtb, therefore, scientists are...
Evidence synthesis and translation of findings for national clinical guideline development: addressing the needs and preferences of guideline development groups
National clinical guidelines aim to help healthcare providers and patients' make decisions about appropriate healthcare. These guidelines use the best available evidence, gathered from national and international research, to develop recommendations on a wide range of topics. These include preventing and managing specific conditions to...
The impact of mutations in PI3K/AKT pathway gene loci on response to PI3K inhibitors
Despite advances in the treatment of breast cancer, the National Cancer Registry of Ireland reported in 2014 that it accounted for 30% of all diagnosed female cancers and 16% of all female cancer deaths. The application of modern technologies to the study of breast cancer has demonstrated that a group of cancer pathways acquire changes...
PRoviding Improved care for Self-harM: a mixed-methods study of intervention, economic and implementation outcomes from a national clinical programme
Suicide is a societal concern in Ireland and is associated with both personal and economic costs. People who self-harm are at particular risk of suicide, and so developing services and interventions for this population can help prevent deaths. Under Ireland's national strategy to reduce suicide, a programme to help people who present...
Engineering RNA-based therapeutics for treatment of sepsis and sepsis induced multiple organ dysfunction syndrome
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Worldwide it affects over 30 million people of all ages and results in 5.3 million deaths annually. In Ireland sepsis contributes to 25% of in-hospital deaths and one in five patients diagnosed with sepsis will die from this disease. To...
Comparison of staphylococcal species from the oro-nasal cavity, periodontal pockets and foot ulcers of patients with type II diabetes: a potential microbial reservoir for diabetic foot ulcer infection
The Research Collaborative in Quality and Patient Safety (RCQPS) is a collaborative initiative between the Health Research Board, the Health Service Executive, National Quality Improvement Team and the Royal College of Physicians of Ireland. It was established in 2013 to advance nationally relevant research in the area of quality and...
Investigating breast cancer risk factors to understand breast cancer epidemiological outcomes
This proposal aims to expand cancer prevention research in Ireland through the assessment of breast cancer risk factors and their influence on clinically relevant characteristics of aggressive breast cancers.Prior research has identified factors associated with increased risk of breast cancer development. One such known factor includes...
Harnessing the power of the Gut-Lung Axis: How Dietary Short-Chain Fatty Acids Balance Inflammatory Outcomes in Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is an incurable lung condition triggered by smoking, or other air pollutants, that leads to long-term lung damage and serious trouble breathing. While COPD is an illness of the lungs, maintaining a healthy gut and a balanced diet can prevent COPD and reduce COPD attacks or flare-ups. But how...
SCaRLeT: Sex differences in Cardiovascular Risk across Life course Transitions
Heart disease is still the leading cause of death around the world. Preventing heart disease, by focusing on risk factors like smoking is essential for improving population health. Females and males do not experience heart disease equally. In adults, research suggests risk factors that can be changed like smoking do not have the same...
Developing a new approach to stroke rehabilitation for the upper limb based on TMS neurofeedback
Today in Ireland, most people who experience a stroke survive, but more than half are left with long-term disabilities due to paralysis of one arm. In the proposed research, we aim to push the boundaries of standard stroke rehabilitation, by introducing a technique that promises to boost the brain's recovery mechanisms, stimulating...
IMPlementation of osteoArthritis Clinical guidelines Together
Osteoarthritis is a disease of the joints, affecting 1 in 8 Irish people as they get older. Due to the growth of our ageing population amongst other reasons, this figure is expected to double within one generation. Most people with the disease in their hips or knees are likely to experience some level of pain as well as difficulty...
Development and validation of diagnostic biomarkers for neurodegenerative conditions based on MRI measures of pathognomonic brain regions
Amyotrophic Lateral Sclerosis (ALS) is a devastating, relentlessly progressive neurodegenerative condition with no effective disease-modifying therapies and no validated biomarkers. Three main themes exist in ALS biomarker research; (1) development of diagnostic indicators, (2) identification of accurate prognostic markers and (3)...
Biomarker discovery and validation in autism spectrum disorder: A study of neonatal cord blood in international birth cohorts
What is Autism? Autism spectrum disorder (ASD) is a complex disorder of brain development. ASD is characterized by difficulties in social interaction, verbal and nonverbal communication and repetitive behaviours. ASD begins in infancy and persists into adolescence and adulthood. ASD imposes significant emotional and economic burdens on...
Using Bayesian network models to predict the impact of public health interventions on disease-prevalence in population health research
Population Health Research studies determinants of health and disease with the goal of identifying interventions that promote health and reduce the burden of disease. Deciding on an appropriate intervention mandates a prior forecast of the intervention's effect on disease. For example, for an intervention targeting smoking, we might...
The Hospital Doctor Retention and Motivation (HDRM) project
Ireland is losing almost as many doctors to emigration as it trains each year. This rate of doctor emigration is a threat to the future of the health system, which may run short of doctors to staff its hospitals. So far, Ireland's solution has been to recruit doctors from other countries. One in three doctors in Ireland is from...
Targeting metabolism for individualised rectal cancer treatment: Development of an omics-led predictive signature of chemoradiation therapy response and novel neoadjuvant therapeutic strategy
Cancer of the rectum is one of the most common cancers in Ireland and worldwide. Patients with rectal cancer are commonly treated with chemoradiation therapy (CRT), which is a combination of chemotherapy and radiation therapy, to shrink the tumour before undergoing surgery to remove the tumour. CRT has been shown to improve survival...
Investigating mitochondrial dysfunction and meta-inflammation as a shared pathogenic network in pre-eclampsia and gestational diabetes mellitus
Pre-eclampsia (PE) and gestational diabetes (GDM) are two common complications of pregnancy. PE is characterised by high blood pressure and increased protein in the urine. GDM develops because the mother's body is not able to produce the extra insulin needed for pregnancy. Together, these pregnancy complications affect 15% of first...
An allostatic load framework for understanding social differences in health and mortality
A consistent finding in the epidemiological literature is that health is socially patterned. On average, individuals from more disadvantaged social backgrounds will develop diseases earlier and will die earlier compared with their more advantaged peers. So ubiquitous is the association between health and wealth that it has been...
Enhancing the evidence base for cost-effectiveness analysis in Ireland: Building improvements from the intervention-specific to system-wide levels
The objective of this research is to increase the relevance and reliability of health economic evidence in Ireland. The aim is to improve the methods for prioritising scarce health funding to the most beneficial uses. This research will translate valuable lessons learnt from cervical cancer prevention to screening for other cancers,...
The liver neighbourhood watch: regulatory tissue-resident natural killer (NK) cells protect against liver decompensation in patients with chronic liver disease
Liver cirrhosis occurs when normal liver tissue is replaced by scar tissue, leading to the eventual failure of normal liver functions. Cirrhosis develops as a result of chronic liver disease, and it accounts for 170,000 deaths annually in Europe and more than 3,000 deaths annually in Ireland. Presently the only treatment is liver...
Targeting adipose tissue inflammation by intermittent hypoxia: towards personalised medicine in obstructive sleep apnoea
Obstructive sleep apnoea (OSA) is a very frequent condition, which is strongly linked with obesity and associated with the development of various heart conditions, such as high blood pressure, heart attack or stroke. It also leads to diseases which are associated with abnormalities in blood glucose levels, such as type 2 diabetes...