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AIIHPC Structured Research Network APA Cycle 2 2019 Applied Partnership Awards Applied Research Projects in Dementia Applying Research into Policy & Practice Postdoctoral Fellowships ARPP 2020 Cancer Prevention Fellowship Programme Cancer Prevention Fellowship Programme Reintegration Grant Capacity Building for Evidence Synthesis Clinical Research Facilities/Centres 2021 Cochrane Training Fellowships Collaborative Doctoral Awards Conference and Event Sponsorship Scheme COVID-19 2020 CSF 2020 DIFA - 2018 DIFA 2017 DIFA 2018 DIFA 2020 DIFA-2018 Emerging Clinician Scientist Awards 2020 Emerging Investigator Awards Emerging Investigator Awards for Health (EIA) 2022 Emerging Investigator Awards Full ERA-NET Cofund for Neuroscience Research (NEURON) ERA-NET Cofund for Personalised Medicine EU Joint Programming Initiative Framework for Safe Nurse Staffing and Skill Mix Health Research Awards Health Research Awards - Definitive Intervention Health Research Awards - Definitive Interventions Health Research Centre HRB Clinical Research Coordination Ireland HRB Clinical Research Facilities HRB Collaboration in Ireland for Clinical Effectiveness Reviews HRB Trials Methodology Research Network HRCI 2020 HRCI-HRB Joint Funding Scheme ICORG Statistics and Data Management Interdisciplinary Capacity Enhancement Awards Investigator Led Projects IPPOSI 2020 Irish Clinical Oncology Research Group Irish Network for Research in Dementia and Neurodegeneration Irish Platform for Patients Organisations Science and Industry Support Award Irish Platform for Patients' Organisations, Science and Industry Joint Programming Initiative Healthy Diet for a Healthy Life Joint Programming Initiative in Neurodegenerative Diseases Joint Programming Initiative on Antimicrobial Resistance Knowledge Exchange and Dissemination Scheme Knowledge Translation Awards Medical Education Research Grant Medical Research Charities Group Support Award MRCG-HRB Joint Funding Scheme National Children's Hospital Foundation Scheme National Clinical Trials Coordination Programme National integrated PhD programme for Medical Practitioners National Intellectual Disability Supplement to TILDA National SpR Academic Fellowship Programme/HRB Joint Funding Scheme National SpR/SR Academic Fellowship Programme Patrick Quinn Awards for Parkinson's Research PPI Ignite Awards Project Development Grants Project Development Grants in Cancer Nursing Research RCQPS COVID-19 Research Collaborative for Quality and Patient Safety Research Collaborative in Quality and Patient Safety Research Leader Awards Research Training Fellowships for Health Professionals Research Training Fellowships for Healthcare Professionals RL FA 2020 RL PA 2020 Secondary Data Analysis Projects SFI-HRB-Wellcome Biomedical Partnership SFI-HRB-Wellcome Research Partnership Structured PhD Programme in Population and Health-Services Research Education Structured PhD Programme in Population Health and Health Services Research The Irish Longitudinal Study on Ageing Trials Methodology Research Network Ulysses Research Visits US-Ireland R&D Partnership Awards WHO-SOLI-2020
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Advanced, automated compound screening for the identification of therapeutic agents in Multiple Sulfatase Deficiency.
Multiple Sulfatase Deficiency (MSD) is an extremely rare, fatal, yet untreatable condition. It is caused by the inherited deficiency of an enzyme (called FGE) that activates a whole family of 17 other cellular enzymes named sulfatases. Sulfatases are indispensable for the degradation of a subset of intracellular molecules. Thus,...