Interventions for improving medication adherence in solid organ transplant recipients

Organ transplantation is the removal of an organ from one individual and placement within another individual. Solid organ transplantation refers to transplantation of the heart, lungs, kidney, pancreas or liver, and successful transplantation involves collaboration across surgical, medical, legal, political and bioethical disciplines. Adequate suppression of the immune system is required for short and long-term survival of the organ transplant, thus immunosuppressive therapy forms the central part of clinical management of an organ transplant recipient. Immunosuppressant strategies and pharmacological agents are similar across all solid organ transplants, most commonly involving oral administration of a calcineurin inhibitor and an antimetabolite, with or without corticosteroids1, in order to sustain a graft free from rejection, and to minimise the potential for graft loss and/or mortality following transplantation.


Award Date
15 September 2016
Award Value
Principal Investigator
Professor Lisa Mellon
Host Institution
Royal College of Surgeons in Ireland
Cochrane Training Fellowships