An investigation of the long-term impact of hypertensive disorders of pregnancy on maternal health, and exploration of optimal models of follow-up care for affected women in Ireland.
Hypertensive disorders of pregnancy (HDP) affect 18 million women annually. It is increasingly recognised that HDP are associated with increased risk of maternal cardiovascular and renal disease. Less is known about the risk of other chronic diseases, particularly those which emerge in older age, such as dementia, retinal vascular disease, and stroke. It is unclear whether patients and healthcare professionals have adequate awareness of links between HDP and chronic disease. It is also unknown whether existing follow-up pathways after HDP are providing adequate opportunities for chronic disease prevention in Ireland.
To investigate the long-term impacts of HDP on the risk of chronic disease in women, and to explore optimal models of follow-up care in Ireland.
- To examine associations between HDP and long-term risk of dementia in a national cohort of parous women
- To synthesise existing evidence on the associations between HDP and long-term risk of retinal vascular disease
- To measure associations between HDP and long-term risk of retinal disease in parous women
- To examine the mediating roles of postpartum hypertension and diabetes in the association of preeclampsia and maternal stroke
- To explore women’s experiences and perceptions of follow-up care in the years after a diagnosis of preeclampsia in Ireland
- To explore doctors’ perceptions and attitudes towards delivery of follow-up care to women after a diagnosis of preeclampsia in Ireland
Objectives 1, 3 and 4 will be addressed using large-scale epidemiological data on over 2 million parous women in the Swedish national registries. Women will be followed up from 1973-2021 inclusive using survival analysis methods. A systematic review will be undertaken to investigate associations between HDP and maternal retinal disorders (Objective 2). Semi-structured qualitative interviews will also be conducted to explore women and doctors’ experiences and perceptions of follow-up care after preeclamptic pregnancy in Ireland (Objectives 5-6).
- Award Date
- 22 September 2023
- Award Value
- Principal Investigator
- Dr Peter Barrett
- Host Institution
- University College Cork
- HRB Postdoctoral Fellowships: CSF 2023