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Early and risky adolescent alcohol use independently predict alcohol, tobacco, cannabis and other drug use in early adulthood in Ireland: a longitudinal analysis of a nationally representative cohort

BACKGROUND: Early and risky adolescent alcohol use have each been associated with adult alcohol consumption. However, it remains unclear whether these behaviours independently predict later-life substance use when considered jointly, and research examining links with substances other than alcohol is limited. This study addresses these gaps by examining longitudinal associations between age at first alcohol […]

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Factors associated with cocaine use at 17 and 20 years old: a longitudinal analysis of a nationally representative cohort

Purpose Despite growing concerns about trends in cocaine use, there is a shortage of longitudinal research that prospectively examines risk and protective factors associated with cocaine initiation and use in general youth populations. This study addresses this gap. Methods Growing Up in Ireland is a nationally representative cohort. Individual, family, and socio-environmental exposures associated with incident past-year […]

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Longitudinal associations between childhood adversity and alcohol use behaviours in early adulthood: examining the mediating roles of parental and peer relationships

BACKGROUND Research has demonstrated positive associations between adverse childhood experiences (ACEs) and alcohol use behaviours in young adults. However, many of these are based on cross-sectional data. The pathway between ACEs and alcohol misuse among emerging adults is not fully understood and there is a lack of data on how parental and peer relationships may […]

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Associations and mediating factors between adverse childhood experiences and substance use behaviours in early adulthood: a population-based longitudinal study

Background: Research has demonstrated positive associations between adverse childhood experiences (ACEs) and substance use behaviours in young adults. However, many of these are based on cross-sectional data. The pathway between ACEs and substance misuse among emerging adults is also not fully understood and few studies have investigated potential mediating factors. Methods: We analysed data from the Child […]

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Predictors and outcomes of adolescent alcohol and drug use: a scoping review

Background Adolescence is a pivotal life stage marked by educational advancement, entry into the workforce and formation of lasting relationships. Globally, adolescence is also the peak period during which individuals first engage in alcohol and/or drug consumption. This scoping review aimed to summarize existing longitudinal research on factors and outcomes related to adolescent substance use […]

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Integrative review on place-based and other geographically defined responses to drug-related threats in communities

Place-based initiatives emerged originally in the field of health, guided by new ideas relating to the social determinants of health, the role of the socioecological context, implementation science, and the importance of community empowerment. Although there are considerable variations, it is possible to identify an underlying model which focuses on providing universal, structural interventions that […]

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Safety and effectiveness of remote pre-hospital triage for appropriate emergency department attendances and service use

The purpose of this systematic review was to provide evidence on the safety and effectiveness of remote pre-hospital triage for reducing unnecessary emergency department (ED) attendances among adults. Remote pre-hospital triage for unscheduled care, sorts patients into appropriate categories or triage dispositions based on how critically ill they are and can be done via telephone, […]

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The efficacy and safety of medicinal cannabis in adult populations: An evidence review

The Medical Cannabis Access Programme in Ireland currently provides access to cannabis to patients with one of three conditions when other treatments have not been successful. The three conditions are spasticity (stiff and/or rigid muscles) associated with multiple sclerosis, nausea and vomiting associated with chemotherapy, and severe epilepsy.   This evidence review was conducted to […]

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