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Validation of blood based samples from the OPTiMiSE (OPtimization of Treatment and Management of Schizophrenia in Europe) study

Schizophrenia is one of the most disabling disease and causes enormous personal, familial and societal cost. Even with more treatment options, there is no guideline on which is the best first choice medication. This means that a lot of people are still suffering even when they are treated. My project’s aim is to fix that by optimising the current treatments and also create new guidelines for
treatment. People with a first episode of psychosis will enter a trial where it will be investigated how effective the current medication are for them. We will be getting a blood sample before treatment enabling us to look for certain proteins in their bloods. The higher presence of these proteins could tell us which patients will respond better to which types of treatment. This information can be used to make a better choice of treating patients.