Sjögren’s is a chronic autoimmune disorder that affects multiple organ systems, primarily targeting the exocrine glands. Although the lacrimal and salivary glands are commonly affected, leading to symptoms such as dryness of the eyes and mouth, it is important for healthcare professionals and the public to recognise that Sjögren’s also has systemic manifestations to avoid underestimating the seriousness of the disease. The pathogenesis of Sjögren’s is complex and multifactorial, involving genetic, environmental, and immunological factors. Sjögren’s has a considerable impact on the quality of life of those affected, impairing their ability to carry out daily activities and negatively affecting their work and social lives. Our previous research and patient and public involvement (PPI) identified that in Ireland, despite affecting 1-in-200 individuals, Sjögren’s symptoms are inadequately recognised and managed. This is also reflected the international literature. This deficiency in awareness and training, coupled with the lack of resourcing and specialist care services, leads to unacceptable delays in diagnosis and appropriate treatment, which can exacerbate complications and negatively impact patient outcomes. From a patient care perspective, there is an urgent need to address these issues and improve Sjögren’s management through increased awareness and better care guidelines. This SYNERG-IE Programme aims to address these challenges through interdisciplinary collaboration between experienced researchers, patients, and knowledge users to (1) optimise prescribing and medicines use (2) use co-design to understand and improve patient care (3) build knowledge and skills for undergraduate students, healthcare professionals, and patients (4) develop policies and national guidance (5) proactively share findings with all relevant stakeholders, and (6) consider pathways forward including how findings translate to other autoimmune diseases and identify future research priorities. The SYNERG-IE Programme will address gaps in Sjögren’s awareness and management, improve patient care, experience, and outcomes and develop a consensus-based roadmap for next steps for future research.
