The structure of the brain is broadly understood however, how well regions are interconnected and where deviations in connectedness result in impairment of function, are only beginning to be studied globally. We will investigate the structural connectivity of networks in the human brain in groups who are either psychiatrically healthy or who have bipolar disorder. We aim to assess the impact of defining the starting points for these connections using the individual’s magnetic resonance brain image (MRI) compared to adapting their images to an atlas. Methodological advances in understanding human brain imaging data can and will yield insight into the brain and how it functions and ultimately benefit people with bipolar disorder.
