The current Ebola outbreak is the largest in history with 22,479 people infected and a death toll of 8,974. The virus has crossed international boundries affecting patients in 9 countries. Currently, there are still active outbreaks in Liberia, Sierra Leone and Guinea. The international focus is currently on containment and prevention of transmission. There are currently no effective approved drugs or vaccinations for Ebola and patients are treated with supportive care focussing on rehydration and treating symptoms. The Ebola virus consists of only seven proteins. Inhibition of any one of these proteins could offer a novel treatment opportunity. This project aims to use 3D computer modelling to match approved drugs and all experimental drugs that have been shown to be safe in early human trials to these Ebola protein targets. The ultimate goal is to identify a drug or safe experimental compound that can quickly be repositioned or re-purposed as a treatment for Ebola.