The conference will focus on evidence-based approaches for embedding innovation into new models of care that are patient-centred in Ireland. Patient-centred models of care mean the patients and their carers are involved in the process planning, implementation and audit of how their illness is managed. These types of models give patients and carer’s a voice and assist with enhancing patient empowerment, leading to better disease management and improved quality of life. The two-day conference seeks to bring together all stakeholders in the delivery of healthcare in Ireland to strengthen national networks of health researchers across the country by providing an opportunity to showcase contemporary, evidence-based research in innovative practices, understand the scope of current health research activity, foster an ethos of collaboration and integration and develop future research agenda for improving health practices and healthcare delivery by moving to a patient-centred approach. This two-day conference delivered both in-person and online, will include applied skills workshops for interested researchers/ clinical professionals and members of patient and carer groups, providing an opportunity to upskill in contemporary research practices in healthcare. An early career research session will afford junior researchers the opportunity to present work-in-progress and get valuable feedback from a panel of experts as well as from representatives of the patient and public community. The second day of the conference will be dedicated to current research in innovation in patient-centred care models and will include leading experts giving keynote presentations as well as thematic sessions from leaders across the Island of Ireland. The conference will also include patient representatives giving perspectives on challenges experienced in the delivery of care across Ireland. Our goal is to develop a successful, inclusive and multidisciplinary health conference for an audience of academics, clinicians, allied healthcare professionals, decisions makers and patients, their carers and the general public.