Pre-announcement: ERA4Health Partnership 2027 (IICS)

The ERA4Health Partnership has pre-announced the launch of the 9th Joint Transnational Call (JTC) “Multi-national Investigator-Initiated Clinical Studies in Cardiovascular, Autoimmune, Metabolic and Non-Communicable Respiratory Diseases, including Underrepresented Populations” (IICS4all 2027).

The Health Research Board (HRB) is participating in the ERA4Health JCT IICS4all 2027, supporting Irish researchers to engage in multi-country Investigator-Initiated Clinical Studies (IICS) that include underrepresented populations).

The call is expected to launch 27 October 2026 with a closing date in January 2027 for pre-proposals.

The aim of the call is to support pragmatic, phase III, randomised controlled, multi-national interventional Investigator-Initiated Clinical Studies (IICS) that meet the following criteria:

1. Study types

• Comparative-effectiveness studies
• Drug repurposing studies of off-patent drugs

2. High public relevance in the following diseases or conditions

• Cardiovascular diseases
• Metabolic disorders
• Autoimmune diseases
• Non-communicable respiratory diseases

3. Inclusivity and diversity

Studies should ensure inclusivity and diversity in the study population and include sex/gender-sensitive, age-specific or other diversity-related aspects, where appropriate.

For further information on the upcoming call, please refer to the IICS4all 2027 preannouncement.