AIIHPC Structured Research Network Applied Partnership Awards Applied Research Projects in Dementia Cancer Prevention Fellowship Programme Cochrane Training Fellowships Collaborative Doctoral Awards Convenor of Cochrane Ireland Award Definitive Intervention and Feasibility Awards Emerging Investigator Awards Framework for Safe Nurse Staffing and Skill Mix Health Research Awards Health Research Awards - Definitive Interventions Health Research Centres HRB Clinical Research Coordination Ireland HRB Clinical Research Facilities HRB Clinical Trials Networks HRB Collaboration in Ireland for Clinical Effectiveness Reviews HRB Trials Methodology Research Network ICORG Statistics and Data Management Interdisciplinary Capacity Enhancement Awards Investigator Led Projects Irish Clinical Oncology Research Group Irish Network for Research in Dementia and Neurodegeneration Irish Platform for Patients Organisations Science and Industry Support Award Joint Programming Initiative Healthy Diet for a Healthy Life Joint Programming Initiative in Neurodegenerative Diseases Joint Programming Initiative on Antimicrobial Resistance Knowledge Exchange and Dissemination Scheme Medical Education Research Grants Medical Research Charities Group Support Award MRCG-HRB Joint Funding Scheme National Children's Hospital Foundation Scheme National Intellectual Disability Supplement to TILDA National SpR/SR Academic Fellowship Programme PPI Ignite Awards Project Development Grants Research Collaborative in Quality and Patient Safety Research Leader Awards Research Training Fellowships for Health Professionals Research Training Fellowships for Healthcare Professionals SFI-HRB-Wellcome Research Partnership Structured PhD Programme in Population and Health-Services Research Education The Irish Longitudinal Study on Ageing Ulysses Research Visits US-Ireland R&D Partnership Awards
Alpha One Foundation Athlone Institute of Technology Beaumont Hospital Cystinosis Foundation Ireland Department of Agriculture, Food and Marine Dublin City University Dublin Dental University Hospital Dublin Institute of Technology Economic and Social Research Institute Fighting Blindness Health Information and Quality Authority HSE - Letterkenny General Hospital HSE - Midland Regional Hospital at Tullamore Irish Cancer Society Irish Clinical Oncology Research Group Ltd Irish Platform for Patients Organisations Science and Industry Irish Thoracic Society Katholieke Universiteit Leuven Mary Immaculate College Limerick Maynooth University Medical Research Charities Group Ltd Molecular Medicine Ireland National Rehabilitation Hospital National Suicide Research Foundation National University of Ireland, Galway National University of Ireland, Maynooth Our Lady's Hospice Royal College of Physicians of Ireland Royal College of Surgeons in Ireland Royal Victoria Eye and Ear Hospital Research Foundation Ltd St John of God's Research Foundation Limited St. James's Hospital Teagasc The Alzheimer Society of Ireland The Children's Medical and Research Foundation Trinity College Dublin University College Cork University College Dublin University of California San Francisco University of Limerick University of Oxford
Spinal muscular atrophy (SMA) is a devastating disease caused by loss of both nerve cells and muscle function. While the nerve is the major affected cell type, therapies specifically aimed at improving muscle function ameliorate survival and/or symptoms in SMA models. Thus,developing muscle-
EMERGE: A randomised placebo controlled trial of the Effectiveness of MEtformin in addition to usual care in the Reduction of GEstational diabetes mellitus effects
Diabetes (high blood sugars) that develops during pregnancy is called Gestational Diabetes Mellitus (GDM). GDM is increasing, affecting one-in-eight pregnant women in Ireland. Women with GDM have an increased risk of complications at the time of delivery, including Caesarean section. Women with GDM have a 7-fold increased risk of...
Cold air plasma to enhance hospital hygiene leading to reduced surface bacterial counts and patient acquisition of vancomycin-resistant enterococci and Clostridium difficile infection
Healthcare-associated infections (HCAI) affect 5-10% of patients admitted to an acute hospital but it is about three times higher in intensive care units (ICUs). Prevention involves many strategies but environmental hygiene is important as many bacterial causes persist on horizontal surfaces, e.g. methicillin-resistant Staphylococcus...
Oral flucloxacillin alone versus flucloxacillin and phenoxymethylpenicillin for the emergency department outpatient treatment of cellulitis: a non-inferiority randomised controlled trial
Acute bacterial skin and skin structure infections (ABSSSIs) are commonly encountered in Emergency Departments (EDs). In Ireland, the most common ABSSSI is cellulitis, which is a spreading bacterial infection of the skin and tissues beneath the skin. Approximately 12 in every 1,000 ED patient attendances in Ireland is due to...
INCA SUn: A prospective randomised multicentre study to optimise the management of symptomatically uncontrolled asthma.
Inhalers are used in the treatment of patients with severe asthma. About 10% of people with asthma fail to achieve control of their asthma symptoms with inhalers. These patients with severe asthma, are often treated with extra medications or have severe attacks. One reason why these patients may not achieve control of their asthma is...
The STRIDER Trial: A randomised controlled trial of sildenafil therapy In dismal prognosis early-onset intrauterine growth restriction
Severe early-onset in utero growth restriction (IUGR) affects babies in womb and is caused by reduced blood flow through the placenta. There is no treatment or cure for IUGR and the current clinical management involves intensive fetal surveillance with elective delivery performed when there is evidence of fetal distress and before the...
Over six thousand people have been diagnosed with HIV infection in Ireland. People living with HIV are now living longer because of effective therapy. However, therapy is life-long and is associated with significant side effects. In addition, immune damage induced by HIV persists even with effective therapy. As a result, people with...
STandaRd Issue TrANsfusion versuS Fresher red blood cell Use in intenSive carE (TRANSFUSE) - a randomised controlled trial.
Red blood cell (RBC) transfusion is required to treat a number of life threatening conditions within the general hospital setting and Intensive Care Units (ICU). Red blood cell units represent a very limited but essential resource. Given the value and relative scarcity of RBC, it is important to ensure its use in the optimal way. A...