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Funding Awarded

3 awards

  • Autophagy induction as a novel therapeutic strategy for MSD

    The lysosomal degradation pathway of autophagy has a crucial role in different pathophysiological conditions, such as infection, neurodegenerative disorders, cancer and ageing. In particular, autophagy plays an important role in the pathophysiology of a family of inborn errors of metabolism due to defect in the activity of lysosomal...

  • Ancient genomics and the Atlantic burden

    WT Scheme: Investigator Award in Science.

    Massive human genome resequencing projects are in train to further the understanding of the genetic contributions to disease. However these offer a limited view of genome genealogies, variant history and past selection, all of which are instrument to the models underpinning genomic...

  • Staphylococcus aureus induced immunosuppressive memory: Consequences for bug and for host

    WT Scheme: Investigator Award in Science.

    Antimicrobial resistance by Staphylococcus aureus is a global epidemic. New approaches based on induction of immune responses that control/prevent S. aureus infection, are required. This necessitates a thorough understanding of the unique relationship cultivated by S. aureus with the...