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HRB Grants and Fellowships

JPND Transnational Call on Pathway Analysis across Neurodegenerative Diseases 2017
Project / Programme grants
Opening Date:
10 January 2017
Closing Date:
6 March 2017


The problem of age-associated neurodegenerative disorders is a growing socio-economic problem in many countries. Over seven million people in Europe suffer from neurodegenerative diseases, yet treatments that prevent or stop the progression of neurodegeneration are still lacking. This places a heavy burden on the individuals with disease, their relatives and society as a whole; a problem that will worsen as the European population inexorably ages. Tackling this ‘grand’ challenge is clearly beyond the scope and resources of any one country. To this end, through HRB, Ireland is currently participating in a member states-led initiative called the EU Joint Programme on Neurodegenerative Disease Research (JPND). The initiative aims to take a more coordinated and coherent approach to funding research that will tackle a range of age-related neurodegenerative diseases, and has agreed a long term Research Strategy comprising basic, clinical and social and healthcare research priorities which is currently being implemented.

There is clinical, genetic and biochemical evidence that similar molecular pathways are relevant in different neurodegenerative and other chronic diseases. Therefore, on January 9th 2017 JPND launched a joint transnational call launched between 21 countries, including Ireland, to support “Multinational Research Projects for Pathway Analysis across Neurodegenerative Diseases

Applications are invited from collaborative consortia of researchers from a minimum of three different countries participating in this call. Irish participants in successful consortia to the “Multinational research projects for Pathway Analysis across Neurodegenerative Diseases” call will be funded through the Health Research Board (HRB), to a maximum of €300,000. The call will be conducted simultaneously by the participating funding organisations in their respective countries and coordinated centrally, with a single proposal submission and peer review system.


  • combine experimental approaches from fundamental, pre-clinical and/or clinical research
  • perform network analyses in different neurodegenerative and/or other chronic diseases to elucidate the underlying common and differing mechanisms between the investigated diseases
  • add value to existing research by analysing diseases across traditional clinical boundaries, technologies and disciplines, thereby gaining deeper understanding of the patho-physiological mechanisms of neurodegenerative diseases.


Proposals submitted under this call may include, but are not limited to, the following types of research:

  •  Examining pathological processes related to neurodegeneration, e.g. by using computational and systems-biology approaches.
  • Defining key regulatory steps affecting the onset or the progression of different diseases

  • Understanding the commonalities and the variability in neurodegenerative and other chronic diseases, using cutting-edge technologies.

  • Identifying common disease pathways and mechanisms.

  • Modelling of multi-level network dysfunction and generating new hypotheses for biological testing.

  • Discovering modulators in order to ultimately determine protective and resilience factors.

  • Identifying new drugs, drug targets or new uses of existing drugs in the treatment of neurodegenerative diseases.

  • Re-defining clinical phenotypes related to neurodegenerative diseases.

Full details of the scope of the call can be found in the call text, accessible from the following link


The total fund for this call is €23m (for all participating countries). The funding available for successful bids involving research carried out in Ireland will be a maximum of €300,000 over 36 months. The maximum amount that funders in each country will contribute for successful consortia can be found on this webpage

Who should apply?

Only research groups from Ireland working in a recognized research institution are eligible for HRB funding in this call. Only joint transnational research projects will be funded. Each proposal must involve groups from at least three different countries participating in this call. For full details on who can apply applicants will need to review the call text and the country-specific requirements on the following website:

Application procedure

Applications must be submitted via the electronic submission system via the following site: ( The call is a two-step application, with a first stage (pre-proposal submission) deadline of March 6th 2017.

Full details on the call for proposals, including scope of the call, evaluation process, eligible costs, and participating countries are available on the call website. 

Please bear in mind that costing of finances in proposals may have to be signed off by the host institution's administrative department. Please allow sufficient time for these additional processes. Any late applications will be rejected.

  • Whilst applications will be submitted jointly by groups from different countries, individual research groups in successful projects will be funded by the individual JPND funding organisation(s) respective of their country.
  • Proposals from Irish institutions that include human Embryonic Stem Cell research will be deemed ineligible
  • The maximum funding for successful partner(s) from HRB in this call is €300,000



  • Closing date for submission is March 6, 2017 22:59 Applications will not be accepted after this time.
  • Funding is anticipated to start from late 2017.  


Where can you get more information about this call?

Full details on the call are available through the call website (

For general enquiries contact the Joint Call Secretariat, whose contact details are listed on that page. 

Applicants from Ireland who still have questions after reading the information on the Call website can contact Dr Ellen Moran at HRB

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