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Motor neuron disease

Download the motor neuron disease research information leaflet and poster

Text from the motor neuron disease leaflet and poster.

Moving towards new treatments for motor neuron disease

Leaflet text.

Understanding how genes are linked with degenerative brain and nerve diseases could lead to better management and treatment.

That's why studies at Beaumont Hospital and Trinity College Dublin are analysing genetic information from patients with the motor neurone disease Amyotrophic lateral sclerosis (ALS), and also from 'controls' who don't have the condition.

Participants give a blood sample, allowing the researchers to build up a DNA bank, and they are currently screening around 1,000 genes of interest.

Meanwhile, work on family histories of patients, also being carried out at Beaumont, is helping to build a more complete picture of neurodegeneration in the Irish population.

'The idea is to understand mechanisms and to try and identify new therapeutic options,' says Beaumont Hospital consultant neurologist and clinician-scientist Prof Orla Hardiman.

'The research draws on a national register of patients with ALS around Ireland, which is maintained by the Irish MND Research Group. Its information provides a valuable resource for studying the processes that underly the disease,' says Prof Hardiman.

We have a very good population-based cohort and there are few countries that can say that.'

Moving towards new treatments for motor neuron disease

Poster text.

  • Researchers at Beaumont are analysing genetic information from patients with the motor neurone disease  Amyotrophic lateral sclerosis (ALS).
  • Genetic analysis could help pinpoint new approaches to the treatment of ALS.
  • The genetic structure of Ireland's population can offer valuable information on disease genetics.
  • A register of patients in Ireland dating back to 1995, provides valuable information for studying neurodegenerative conditions.
  • Studies of family histories are linking with genetic research to build more understanding of the conditions.

'We have a very good population-based cohort and there are few countries that can say that'. Prof Orla Hardiman - Beaumont hospital consultant neurologist and HRB clinician-scientist.

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